Publications

Publications

Publications


Recent Publications

J. S. Biggs, M. Watkins, N. Puillandre, J.P. Ownby, E. Lopez-Vera, S. Christensen, K. J. Moreno, A. L. Navarro, P. C. Showers, and Baldomero M. Olivera. Evolution of Conus Peptide Toxins: Analysis of Conus californicus Reeve, 1844. Molecular Phylogenetics and EvolutionIn press.

J. S. Biggs, M. Watkins, P. C. Showers, and B. M. Olivera. (2010) Defining a Clade by Morphological, Molecular and Toxinological Criteria: Distinctive Forms related toConus praecellens A. Adams, 1854. Nautilus. 124(1), 1-19.

Peraud O., Biggs J.S., Hughen R.W., Light A.R., Concepcion G.P., Olivera B.M., and E.W. Schmidt (2009) Microhabitats within venomous cone snails yield diverse actinobacteria. Applied and Environmental Microbiology. 75(21), 6820–6826.

J.S. Biggs, Olivera B.M., and Y.I. Kantor (2008) Alpha-conopeptides specifically expressed in the salivary gland of Conus pulicariusToxicon. Jul;52(1):101-5.

J.S. Biggs, Rosenfeld, Y., Shai, Y., and B. M. Olivera. (2007) Conolysin-Mt: A ConusPeptide that Disrupts Cellular Membranes. Biochemistry, 46(44), 12586-12593.

J.S. Biggs, Jie Wan, N. Shane Cutler, Jukka Hakkola, Päivi Uusimäki, Hannu Raunio, and Garold S. Yost. (2007) Transcription Factor Binding to a Double E-Box Motif Represses CYP3A4 Expression in Human Lung Cells. Molecular Pharmacology, 72, 514-525.

Biggs, J.S. (2005) Lung-Selective Regulation of the Human CYP3A Genes. Ph.D. Dissertation. University of Utah, Salt Lake City, Utah 84112.

Matsumoto S.S., Biggs J.S., Copp, B.R., Holden, J.A. and L.R. Barrows . (2003)  Mechanism of ascididemin-induced cytotoxicity.  Chemical Research in Toxicology, 16, 113-122.

Puglisi, M.P., Paul, V.J., Biggs, J.S., and M. Slattery (2002) Co-occurrence of chemical and structural defenses in the gorgonian corals of Guam. Marine Ecology Progress Series 239:105-114.

J.S. Biggs (2000) The Role of Secondary Metabolite Complexity in the Red AlgaLaurencia palisada as a Defense Against Diverse Consumers. Thesis. University of Guam Marine Laboratory. Mangilao, Guam 96923.

Harrigan, G., Luesch, H., Yoshida, W.Y., Moore, R.E., Nagle, D.G., BiggsJ.S., Park, P.U., and V.J. Paul. (1999)  Tumonoic Acids, Novel Metabolites from a Cyanobacterial Assemblage of Lyngbya majuscula and Schizothrix calcicola.  Journal of Natural Products. Vol. 62. Pp. 464-467.

Harrigan, G., Yoshida, W.Y., Moore, R.E., Nagle, D.G., Park, P.U., Biggs, J.S., Paul, V.J., Mooberry, S.L., Corbett, T.H., and F.A. Valeriote (1998)  Isolation, Structure Determination, and Biological Activity of Dolastatin 12 and Lyngbyastatin 1 FromLyngbya majuscula/Schizothrix calcicola Cyanobacterial Assemblages. Journal of Natural Products. Vol.61. Pp. 1221-1225.